https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Nitrogen-promoted molybdenum dioxide nanosheets for electrochemical hydrogen generation https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36477 2 sheets with excellent stable Pt-like HER performance. A simple and repeatable strategy has been developed via the use of the cheap, simple small organic molecule urea as a reducing agent. We confirm that N doping can induce a disordered surface lattice and increase the number of proton adsorption sites with a relatively weak binding force. Owing to the cooperative effects of surface N doping, disordered surface distortion and the intrinsic nature of MoO2, high HER activity can be achieved, with an overpotential of η = 96 mV vs. RHE at a current density of −10 mA cm−2 and a Tafel slope of 33 mV per decade. Moreover, we further extended the synthesis method to Ni and Co systems with the formation of N–NiO/Ni and N–CoO/Co core–shell structures, which exhibited enhanced HER performance in comparison with bare MO/M (M = metal) samples. This study can help us design new earth-abundant electrocatalysts with further enhancements in catalytic performance.]]> Tue 19 May 2020 13:15:39 AEST ]]> Exploring the genetics of irritable bowel syndrome: a GWA study in the general population and replication in multinational case-control cohorts https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26934 KDELR2 (KDEL endoplasmic reticulum protein retention receptor 2) and GRID2IP (glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein), showed consistent IBS risk effects in the index GWAS and all replication cohorts and reached p=9.31×10-6 in a meta-analysis of all datasets. Several SNPs in this region are associated with cis effects on KDELR2 expression, and a trend for increased mucosal KDLER2 mRNA expression was observed in IBS cases compared with controls. Conclusions: Our results demonstrate that general population-based studies combined with analyses of patient cohorts provide good opportunities for gene discovery in IBS. The 7p22.1 and other risk signals detected in this study constitute a good starting platform for hypothesis testing in future functional investigations.]]> Sat 24 Mar 2018 07:27:31 AEDT ]]>